Technology
In more than 30 animal studies, SentrX products have been consistently shown to promote healing-even in the most difficult-to-treat cases. Why? It comes down to cells.
Proven Revolutionary Animal Wound Healing Technology
Enhanced wound healing in horses and dogs using crosslinked hyaluronic acid-based hydrogel films.
Poster presented at the Society for Biomaterials Annual Meeting, Chicago, IL, April 2007.
Mann BK, Scott JA, Rees R, Brown J, Seppi M, Burns G, Prestwich GD.
Glycosaminoglycan Hydrogels as Supplemental Wound Dressings for Donor Sites
Journal of Burn Care & Rehabilitation. 25(3):276-286, May/June 2004.
Kirker, K. R. BSE; Luo, Y. PhD; Morris, S. E. MD; Shelby, J. PhD; Prestwich, G. D. PhD
Blycosaminogycan Hydrogel Films as Biointeractive Dressings for Wound Healing
Biomaterials, 23, 3661 3671 (2002)
Kirker, K. R. BSE; Luo, Y. PhD; J.H. Nielson, Shelby, J. PhD; Prestwich, G. D. PhD
Chrondroitin Sulfate Hydrogel and Wound Healing in Rabbit Maxillary Sinus Mucosa
Laryngoscope, 114, 1406-1409 (2004)
M.E. Guilbert, K.R. Kirker, S.D. Gray, P.D. Ward, J.G. Szakacs, G.D. Prestwich, and R.R. Orlandi
Accelerated Repair of Cortical Bone Defects Using a Synthetic Extracellular Matrix to Deliver Human Demineralized Bone Matrix
J Orthop Res 24:1454-1462, 2006
Yanchun Liu, Shama Ahmad, Xiao Zheng Shu, R. Kent Sanders, Sally Anne Kopesec, Glenn D. Prestwich
Disulfide Cross-Linked Hyaluronan Hydrogels
Biomacromolecules, 3, 1304 -1311, 2002
Xiao Zheng Shu, Yanchun Liu, Yi Luo, Meredith C. Roberts, and Glenn D. Prestwich
Disulfide-crosslinked hyaluronan-gelatin hydrogel films: a covalent mimic of the extracellular matrix for in vitro cell growth.
Biomaterials 2003 Sep;24(21):3825-34
Xiao Zheng Shu, Yanchun Liu, Glenn D. Prestwich, and F. Palumbo
Disulfide-crosslinked hyaluronan-gelatin sponge: Growth of fibrous tissue in vivo
Journal of Biomedical Materials Research Part A Volume 68A, Issue 1 , Pages 142 - 149
Yanchun Liu, Xiao Zheng Shu, Steven D. Gray, Glenn D. Prestwich
In situ crosslinkable hyaluronan hydrogels for tissue engineering
Biomaterials 2004 Mar-Apr;25(7-8):1339-48
Zheng Sh X, Liu Y, Palumbo FS, Luo Y, Prestwich GD
Composite Articular Cartilage Engineered on a Chondrocyte-Seeded Aliphatic Polyurethane Sponge
Tissue Engineering Jul 2004, Vol. 10, No. 7 : 1084 -1092
Yanchun Liu, Ken Webb, Kelly R. Kirker, Nicole J. Bernshaw, Patrick A. Tresco, Steven D. Gray, Glenn D. Prestwich
Crosslinked hyaluronan hydrogels containing mitomycin C reduce postoperative abdominal adhesions
Fertility and Sterility, Volume 83, Issue 4, Pages 1275-1283
Y. Liu, H. Li, X. Shu, S. Gray, G. Prestwich
Composition of hyaluronan affects wound healing in the rabbit maxillary sinus
American Journal of Rhinology, Volume 20, Number 2, March-April 2006, pp. 206-211(6)
Proctor, Matthew; Proctor, Kerry; Shu, Xiao Zheng; McGill, Lawrence D.; Prestwich, Glenn D.; Orlandi, Richard R.
Biocompatibility and stability of disulfide-crosslinked hyaluronan films
Biomaterials. 2005 Aug;26(23):4737-46.Click here to read
Liu Y, Zheng Shu X, Prestwich GD.
Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor
Biomaterials. 2005 Oct;26(30):6054-67. Epub 2005 Apr 22.Click here to read
Cai S, Liu Y, Zheng Shu X, Prestwich GD.
Fibronectin Functional Domains Coupled to Hyaluronan Stimulate Adult Human Dermal Fibroblast Responses Critical for Wound Healing
Tissue Engineering Mar 2006, Vol. 12, No. 3 : 601 -613
Kaustabh Ghosh, Xiang-Dong Ren, Xiao Zheng Shu, Glenn D. Prestwich, Richard A.F. Clark
Rheological Characterization of in Situ Cross-Linkable Hyaluronan Hydrogels
Biomacromolecules, 6 (5), 2857 -2865, 2005. 10.1021/bm050361c S1525-7797(05)00361-2
Kaustabh Ghosh, Xiao Zheng Shu, Robert Mou, Jack Lombardi, Glenn D. Prestwich, Miriam H. Rafailovich, and Richard A. F. Clark
Dual growth factor-induced angiogenesis in vivo using hyaluronan hydrogel implants
Biomaterials. 2006 Mar;27(9):1868-75. Epub 2005 Oct 21.Click here to read
Peattie RA, Rieke ER, Hewett EM, Fisher RJ, Shu XZ, Prestwich GD
Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering
Journal of Biomedical Materials Research Part A, Volume 79A, Issue 4, Pages 902 - 912
Xiao Zheng Shu, Shama Ahmad, Yanchun Liu, Glenn D. Prestwich
Molecular Stenting with a Crosslinked Hyaluronan Derivative Inhibits Collagen Gel Contraction
Journal of Investigative Dermatology (2006) 126, 2202–2209. doi:10.1038/sj.jid.5700380;
Tanuj D Mehra1, Kaustabh Ghosh, Xiao Zheng Shu, Glenn D Prestwich, and Richard A F Clark
Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF
Biomaterials. 2006 Oct;27(30):5242-51. Epub 2006 Jun 30.Click here to read
Pike DB, Cai S, Pomraning KR, Firpo MA, Fisher RJ, Shu XZ, Prestwich GD, Peattie RA
Stimulation of in vivo angiogenesis using dual growth factor-loaded crosslinked glycosaminoglycan hydrogels
Biomaterials. 2006 Dec;27(35):5935-43. Epub 2006 Sep 6
Riley CM, Fuegy PW, Firpo MA, Shu XZ, Prestwich GD, Peattie RA.
Book Chapters
Reduced Post-operative Intra-abdominal Adhesions Using Carbylan TM-SX, a Semi-synthetic Glycosaminoglycan Hydrogel
Fertility and Sterility,Volume 83,Issue 4,Pages 1275-1283
Y. Liu, H. Li, X. Shu, S. Gray, G. Prestwich
Injectable synthetic extracellular matrices for tissue engineering and repair
Adv Exp Med Biol. 2006;585:125-33.
Prestwich GD, Shu XZ, Liu Y, Cai S, Walsh JF, Hughes CW, Ahmad S, Kirker KR, Yu B, Orlandi RR, Park AH, Thibeault SL, Duflo S, Smith ME.
